- 1 2020
- 2 2019
- 2.1 Drs. Montserrat Navarro and Todd Thiele are co-authors on a clinical trial paper that assessed a potential novel treatment to curb problematic binge drinking in humans, published in Alcohol and Alcoholism
- 2.2 Sophie Bendrath joins the Lab!
- 2.3 Stacey Robinson publishes in Brain Sciences
- 2.4 Nathan Burnham successfully defends his Ph.D. dissertation
- 2.5 Thiele Lab Coordinator, Rhiannon Thomas, is awarded a 2019 Psychology & Neuroscience Staff Excellence Award
- 2.6 Michel Companion is awarded an F31 pre-doctoral fellowship
- 2.7 The lab welcomes two new postdoctoral fellows
- 2.8 Stacey Robinson publishes in Neuropsychopharmacology
- 2.9 Montserrat Navarro publishes in Alcoholism: Clinical & Experimental Research
- 3 2018
The Thiele Lab published two review articles, one on the melanocortin system as a potential target for treating alcohol use disorders (in Brain Research) and the second on the role of the neuropeptide, somatostatin, in modulating substance abuse and affective disorders (in Neuropharmacology).
Dr. Jose Manual Lerma-Cabrera was lead author of a recent review article that highlighted evidence for the melanocortin neuropeptide system as a promising target for treating alcohol use disorders, which was published in Brain Research. Additionally, Dr. Stacey Robinson was lead author of a review article published in Neuropharmacology that highlighted the role of the neuropeptide, somatostatin, in modulating affective disorders, and made a case for somatostatin as a potential candidate for modulating neurobiological responses to alcohol.
Drs. Montserrat Navarro and Todd Thiele co-authored a clinical trial paper describing a study that assessed the efficacy of novel treatment for binge drinking in humans, published in Alcohol and Alcoholism. This open-label study, based on their pre-clinical studies, provides evidence that combined therapy with naltrexone and bupropion may help reduce binge drinking in humans, a novel approach to treating alcohol use disorders.
Sophie Bendrath joins the Lab!
Sophie earned her degree from Rutgers University during her undergraduate studies. She is currently studying how certain neuropeptides, particularly in the limbic system, can modulate binge drinking behavior. Welcome to the team, Sophie!
Stacey Robinson publishes in Brain Sciences
Dr. Stacey Robinson, a postdoctoral fellow in the Behavioral & Integrative Neuroscience Program, is lead author on a paper recently published in Brain Sciences. Her work provides novel evidence that corticotropin releasing factor (CRF) signaling in the medial prefrontal cortex (mPFC) via CRF type 1 and type 2 receptors modulates binge like ethanol intake in mice.
Nathan Burnham successfully defends his Ph.D. dissertation
Dr. Nathan Burnham successfully defended his dissertation proposal and has earned his Ph.D., outstanding work Nathan! His novel research shows that a norepinephrine neurocircuit from the locus coeruleus to the lateral hypothalamus modulates binge alcohol drinking and food intake in mice. Nathan will next begin postdoctoral training at North Carolina State University in the lab of Dr. Leslie Sombers.
Thiele Lab Coordinator, Rhiannon Thomas, is awarded a 2019 Psychology & Neuroscience Staff Excellence Award
Ms. Rhiannon Thomas, the Lab Coordinator in the Thiele laboratory, received a 2019 Psychology & Neuroscience Staff Excellence Award. This award recognizes superb customer service, initiative, teamwork, and overall excellence. Rhiannon received $1,000, a plaque recognizing her achievement, and her name will be displayed along with other award winners from years past in the Davie Hall lobby. Congratulations Rhiannon!
Michel Companion is awarded an F31 pre-doctoral fellowship
Mr. Michel Companion, a graduate student in the Behavioral & Integrative Neuroscience Program, received a two-year F31 predoctoral fellowship from that National Institute on Alcohol Abuse and Alcoholism to study the role of a neuropeptide Y (NPY) type-1 receptor-expressing neuronal circuit from the central amygdala to the lateral habenula in the modulation of binge alcohol drinking. Excellent work Michel!
The lab welcomes two new postdoctoral fellows
Drs. Ana Paula Segantine Dornellas Loper and Christa Houck have joined the lab. Dr. Ana Paula Segantine Dornellas Loper received her Ph.D. at the Universidade Federal de São Paulo in Brazil, and Dr. Christa Houck received her Ph.D. from Indiana University—Purdue University at Indianapolis. Welcome to the team!
Stacey Robinson publishes in Neuropsychopharmacology
Dr. Stacey Robinson, a postdoctoral fellow in the Behavioral & Integrative Neuroscience Program, is lead author on a paper recently published in Neuropsychopharmacology. Her work provides novel evidence the neuropeptide Y (NPY) signaling in the medial prefrontal cortex (mPFC), and in an NPY type-1 receptor-expression circuit form the mPFC to the basolateral amygdala, modulate binge alcohol drinking.
Dr. Montserrat Navarro, an Associate Research Professor in the Behavioral & Integrative Neuroscience Program, is the lead author on a paper recently published in Alcoholism: Clinical & Experimental Research. Her work provides the first proof-of-concept work in animal models suggesting that the drug, bupropion, may have therapeutic value for treating alcohol use disorder, particularly problematic binge drinking. This work is part of a collaboration that is currently assessing the ability of bupropion to curb binge drinking in a clinical trial experiment with humans.
Michel Companion successfully defends his master’s thesis
Mr. Michel Companion successfully defended his master’s thesis, great job Michel! His work showed that silencing a GABAergic circuit originating in the bed nucleus of the stria terminalis and innervating the ventral tegmental area protects against binge alcohol drinking. This work was recently published in the European Journal of Neuroscience.
Nathan Burnham publishes in Neuroscience
Mr. Nathan Burnham, a graduate student in the Behavioral & Integrative Neuroscience Program, is lead author on a paper published in Neuroscience. Nathan’s study identifies that brain regions that are activated in mice that are binge drinking alcohol and provides a valuable roadmap for futures studies that will investigate the neurocircuitry that modulates binge drinking.
Honoreé Brewton receives a Dashiell Travel Award
Ms. Honoreé Brewton, a graduate student in the Behavioral & Integrative Neuroscience Program, received a Dashiell Research Fund Travel Award, congratulations Honoree!