Publications

Center Line Articles

Thiele Laboratory Neuropeptide Research Reveals Therapeutic Targets for Alcoholism (Vol. 18, No 3, 2007)

Alcoholism and Obesity: Overlapping Brain Pathways? (Vol. 14, No. 1, 2003)

Psychologist Probes the Genetic Secrets of Uncontrollable Drinking (Vol. 13, No.1, 2002)

Recent Publications

Click here for a list of publications from PubMed

MC4-R signaling within the nucleus accumbens shell, but not the lateral hypothalamus, modulates ethanol palatability in rats. Lerma-Cabrera JM, Carvajal F, Chotro G, Gaztañaga M, Navarro M, Thiele TE, Cubero I. Behav Brain Res. 2013 Feb 15;239:51-4.

Decreased Immunoreactivity of the Polypeptide Precursor Pro-Opiomelanocortin (POMC) and the Prohormone Convertase PC1/3 After Chronic Ethanol Exposure in Sprague-Dawley Rats. Navarro M, Cubero I, Thiele TE. Alcohol Clin Exp Res. 2012 Oct 10.

Control of food intake by MC4-R signaling in the lateral hypothalamus, nucleus accumbens shell and ventral tegmental area: interactions with ethanol. Lerma-Cabrera JM, Carvajal F, de la Torre L, de la Fuente L, Navarro M, Thiele TE, Cubero I. Behav Brain Res. 2012 Sep 1;234(1):51-60.

Corticotropin releasing factor signaling in the central amygdala is recruited during binge-like ethanol consumption in C57BL/6J mice. Lowery-Gionta EG, Navarro M, Li C, Pleil KE, Rinker JA, Cox BR, Sprow GM, Kash TL, Thiele TE. J Neurosci. 2012 Mar 7;32(10):3405-13.

Central neuropeptide Y modulates binge-like ethanol drinking in C57BL/6J mice via Y1 and Y2 receptors. Sparrow AM, Lowery-Gionta EG, Pleil KE, Li C, Sprow GM, Cox BR, Rinker JA, Jijon AM, Peňa J, Navarro M, Kash TL, Thiele TE. Neuropsychopharmacology. 2012 May;37(6):1409-21.

Neuropeptide Y signaling modulates the expression of ethanol-induced behavioral sensitization in mice. Hayes DM, Fee JR, McCown TJ, Knapp DJ, Breese GR, Cubero I, Carvajal F, Lerma-Cabrera JM, Navarro M, Thiele TE. Addict Biol. 2012 Mar;17(2):338-50.

Assessment of voluntary ethanol consumption and the effects of a melanocortin (MC) receptor agonist on ethanol intake in mutant C57BL/6J mice lacking the MC-4 receptor. Navarro M, Lerma-Cabrera JM, Carvajal F, Lowery EG, Cubero I, Thiele TE. Alcohol Clin Exp Res. 2011 Jun;35(6):1058-66.

Neuropeptide Y conjugated to saporin alters anxiety-like behavior when injected into the central nucleus of the amygdala or basomedial hypothalamus in BALB/cJ mice. Lyons AM, Thiele TE. Peptides. 2010 Dec;31(12):2193-9.

CRF-1 antagonist and CRF-2 agonist decrease binge-like ethanol drinking in C57BL/6J mice independent of the HPA axis. Lowery EG, Spanos M, Navarro M, Lyons AM, Hodge CW, Thiele TE. Neuropsychopharmacology. 2010 May;35(6):1241-52.

The alcohol deprivation effect in C57BL/6J mice is observed using operant self-administration procedures and is modulated by CRF-1 receptor signaling. Sparta DR, Ferraro FM 3rd, Fee JR, Knapp DJ, Breese GR, Thiele TE. Alcohol Clin Exp Res. 2009 Jan;33(1):31-42.

Effects of food availability and administration of orexigenic and anorectic agents on elevated ethanol drinking associated with drinking in the dark procedures. Lyons AM, Lowery EG, Sparta DR, Thiele TE. Alcohol Clin Exp Res. 2008 Nov;32(11):1962-8.

Lowery EG, Sparrow AM, Breese GR, Knapp DJ, Thiele TE. The CRF-1 receptor antagonist, CP-154,526, attenuates stress-induced increases in ethanol consumption by BALB/cJ mice. Alcohol Clin Exp Res. 2008 Feb;32(2):240-8.

Sparta DR, Sparrow AM, Lowery EG, Fee JR, Knapp DJ, Thiele TE. Blockade of the corticotropin releasing factor type 1 receptor attenuates elevated ethanol drinking associated with drinking in the dark procedures. Alcohol Clin Exp Res. 2008 Feb;32(2):259-65.

Navarro M, Cubero I, Knapp DJ, Breese GR, Thiele TE. Decreased immunoreactivity of the melanocortin neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) after chronic ethanol exposure in Sprague-Dawley rats. Alcohol Clin Exp Res. 2008 Feb;32(2):266-76.

Fee JR, Sparta DR, Picker MJ, Thiele TE. Corticotropin releasing factor-1 receptor antagonist, CP-154,526, blocks the expression of ethanol-induced behavioral sensitization in DBA/2J mice. Neuroscience. 2007 Sep 8.
Sparta DR, Fee JR, Knapp DJ, Breese GR, Thiele TE. Elevated anxiety-like behavior following ethanol exposure in mutant mice lacking neuropeptide Y (NPY). Drug Alcohol Depend. 2007 Oct 8;90(2-3):297-300. Epub 2007 May 4.

Ferraro FM 3rd, Sparta DR, Knapp DJ, Breese GR, Thiele TE.  Increased consumption but not operant self-administration of ethanol in mice lacking the RIIbeta subunit of protein kinase A.  Alcohol Clin Exp Res. 2006 May;30(5):825-35.

Fee JR, Knapp DJ, Sparta DR, Breese GR, Picker MJ, Thiele TE. Involvement of protein kinase A in ethanol-induced locomotor activity and sensitization. Neuroscience. 2006 Jun 19;140(1):21-31.

van Dijk G, de Vries K, Nyakas C, Buwalda B, Adage T, Kuipers F, Kas MJ, Adan RA, Wilkinson CW, Thiele TE, Scheurink AJ. Reduced anorexigenic efficacy of leptin, but not of the melanocortin receptor agonist melanotan-II, predicts diet-induced obesity in rats.  Endocrinology. 2005 Dec;146(12):5247-56.