Recent Publications

Click here for a full list of publications from PubMed

Extended Amygdala to Ventral Tegmental Area Corticotropin-Releasing Factor Circuit Controls Binge Ethanol Intake. Rinker JA, Marshall SA, Mazzone CM, Lowery-Gionta EG, Gulati V, Pleil KE, Kash TL, Navarro M, Thiele TE. Biol Psychiatry. 2016 Mar 3. pii: S0006-3223(16)30006-3. doi: 10.1016/j.biopsych.2016.02.029.

Lateral Hypothalamus GABAergic Neurons Modulate Consummatory Behaviors Regardless of the Caloric Content or Biological Relevance of the Consumed Stimuli. Navarro M, Olney JJ, Burnham NW, Mazzone CM, Lowery-Gionta EG, Pleil KE, Kash TL, Thiele TE. Neuropsychopharmacology. 2015 Oct 7. doi: 10.1038/npp.2015.304.

IL-1 receptor signaling in the basolateral amygdala modulates binge-like ethanol consumption in male C57BL/6J mice. Marshall SA, Casachahua JD, Rinker JA, Blose AK, Lysle DT, Thiele TE.   Brain Behav Immun. 2015 Sep 10. pii: S0889-1591(15)30013-1. doi: 10.1016/j.bbi.2015.09.006.

Assessment of the Effects of 6 Standard Rodent Diets on Binge-Like and Voluntary Ethanol Consumption in Male C57BL/6J Mice. Marshall SA, Rinker JA, Harrison LK, Fletcher CA, Herfel TM, Thiele TE. Alcohol Clin Exp Res. 2015 Aug;39(8):1406-16. doi: 10.1111/acer.12773. Epub 2015 Jun 25.

Evidence that Melanocortin Receptor Agonist Melanotan-II Synergistically Augments the Ability of Naltrexone to Blunt Binge-Like Ethanol Intake in Male C57BL/6J Mice. Navarro M, Carvajal F, Lerma-Cabrera JM, Cubero I, Picker MJ, Thiele TE. Alcohol Clin Exp Res. 2015 Aug;39(8):1425-33. doi: 10.1111/acer.12774. Epub 2015 Jun 24.

Lateral hypothalamic melanocortin receptor signaling modulates binge-like ethanol drinking in C57BL/6J mice. Sprow GM, Rinker JA, Lowery-Gointa EG, Sparrow AM, Navarro M, Thiele TE. Addict Biol. 2015 May 15. doi: 10.1111/adb.12264.

NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking. Pleil KE, Rinker JA, Lowery-Gionta EG, Mazzone CM, McCall NM, Kendra AM, Olson DP, Lowell BB, Grant KA, Thiele TE, Kash TL. Nat Neurosci. 2015 Apr;18(4):545-52. doi: 10.1038/nn.3972. Epub 2015 Mar 9.

Binge-like consumption of ethanol and other salient reinforcers is blocked by orexin-1 receptor inhibition and leads to a reduction of hypothalamic orexin immunoreactivity. Olney JJ, Navarro M, Thiele TE. Alcohol Clin Exp Res. 2015 Jan;39(1):21-9. doi: 10.1111/acer.12591.

Histone acetylation in the nucleus accumbens shell modulates ethanol-induced locomotor activity in DBA/2J mice. Sprow GM, Rinker JA, Thiele TE. Alcohol Clin Exp Res. 2014 Sep;38(9):2377-86. doi: 10.1111/acer.12502. Epub 2014 Aug 4.

“Drinking in the Dark” (DID): a simple mouse model of binge-like alcohol intake. Thiele TE, Crabbe JC, Boehm SL 2nd. Curr Protoc Neurosci. 2014 Jul 1;68:9.49.1-9.49.12. doi: 10.1002/0471142301.ns0949s68.

Altered GABAA receptor expression and seizure threshold following acute ethanol challenge in mice lacking the RIIβ subunit of PKA. Carlson SL, O’Buckley TK, Thomas R, Thiele TE, Morrow AL. Neurochem Res. 2014 Jun;39(6):1079-87. doi: 10.1007/s11064-013-1167-0. Epub 2013 Oct 9.

“Drinking in the dark” (DID) procedures: a model of binge-like ethanol drinking in non-dependent mice. Thiele TE, Navarro M. Alcohol. 2014 May;48(3):235-41. doi: 10.1016/j.alcohol.2013.08.005. Epub 2013 Oct 29. Review.

The protective effects of the melanocortin receptor (MCR) agonist, melanotan-II (MTII), against binge-like ethanol drinking are facilitated by deletion of the MC3 receptor in mice. Olney JJ, Sprow GM, Navarro M, Thiele TE. Neuropeptides. 2014 Feb;48(1):47-51. doi: 10.1016/j.npep.2013.11.001. Epub 2013 Nov 15.

Repeated binge-like ethanol drinking alters ethanol drinking patterns and depresses striatal GABAergic transmission. Wilcox MV, Cuzon Carlson VC, Sherazee N, Sprow GM, Bock R, Thiele TE, Lovinger DM, Alvarez VA. Neuropsychopharmacology. 2014 Feb;39(3):579-94. doi: 10.1038/npp.2013.230. Epub 2013 Sep 2.

Targeting central melanocortin receptors: a promising novel approach for treating alcohol abuse disorders. Olney JJ, Navarro M, Thiele TE. Front Neurosci. 2014 Jun 3;8:128. doi: 10.3389/fnins.2014.00128. eCollection 2014. Review.